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Based on data from 2 participants, Sleep Cycles is generally highest after a daily total of 6100 milligrams of Acetyl L-carnitine intake over the previous 7 days.
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People with higher Acetyl L-carnitine intake usually have lower Sleep Cycles
Each column represents the number of days this value occurred.
This chart shows the typical value recorded for Acetyl L-carnitine on each day of the week.
This chart shows the typical value recorded for Acetyl L-carnitine for each month of the year.
Each column represents the number of days this value occurred.
This chart shows the typical value recorded for Sleep Cycles on each day of the week.
This chart shows the typical value recorded for Sleep Cycles for each month of the year.

Abstract

Aggregated data from 2 study participants suggests with a high degree of confidence (p=0.025360547820652, 95% CI -0.955 to 1.044) that Acetyl L-carnitine has a very weakly positive predictive relationship (R=0.04) with Sleep Cycles. The highest quartile of Sleep Cycles measurements were observed following an average 12 milligrams Acetyl L-carnitine per day. The lowest quartile of Sleep Cycles measurements were observed following an average 5602.3340248963 mg Acetyl L-carnitine per day.

Objective

The objective of this study is to determine the nature of the relationship (if any) between Acetyl L-carnitine and Sleep Cycles. Additionally, we attempt to determine the Acetyl L-carnitine values most likely to produce optimal Sleep Cycles values.

Participant Instructions

Record your Acetyl L-carnitine daily in the reminder inbox or using the interactive web or mobile notifications.
Get Sleep as Android here and use it to record your Sleep Cycles. Once you have a Sleep as Android account, you can import your data from the Import Data page. This individual's data will automatically be imported and analyzed.

Design

This study is based on data donated by 2 participants. Thus, the study design is equivalent to the aggregation of 2 separate n=1 observational natural experiments.

Data Analysis

Acetyl L-carnitine Pre-Processing
Acetyl L-carnitine measurement values below 0 milligrams were assumed erroneous and removed. No maximum allowed measurement value was defined for Acetyl L-carnitine. It was assumed that any gaps in Acetyl L-carnitine data were unrecorded 0 milligrams measurement values.
Acetyl L-carnitine Analysis Settings

Sleep Cycles Pre-Processing
Sleep Cycles measurement values below 0 event were assumed erroneous and removed. No maximum allowed measurement value was defined for Sleep Cycles. It was assumed that any gaps in Sleep Cycles data were unrecorded 0 event measurement values.
Sleep Cycles Analysis Settings

Predictive Analytics
It was assumed that 0.5 hours would pass before a change in Acetyl L-carnitine would produce an observable change in Sleep Cycles. It was assumed that Acetyl L-carnitine could produce an observable change in Sleep Cycles for as much as 7 days after the stimulus event.
Predictive Analysis Settings

Data Sources

Acetyl L-carnitine data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Sleep Cycles data was primarily collected using Sleep as Android. Smart alarm clock with sleep cycle tracking. Wakes you gently in optimal moment for pleasant mornings.

Limitations

As with any human experiment, it was impossible to control for all potentially confounding variables. Correlation does not necessarily imply causation. We can never know for sure if one factor is definitely the cause of an outcome. However, lack of correlation definitely implies the lack of a causal relationship. Hence, we can with great confidence rule out non-existent relationships. For instance, if we discover no relationship between mood and an antidepressant this information is just as or even more valuable than the discovery that there is a relationship.
We can also take advantage of several characteristics of time series data from many subjects to infer the likelihood of a causal relationship if we do find a correlational relationship. The criteria for causation are a group of minimal conditions necessary to provide adequate evidence of a causal relationship between an incidence and a possible consequence.

The list of the criteria is as follows:
Strength (A.K.A. Effect Size)
A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal. There is a very weakly positive relationship between Acetyl L-carnitine intake and Sleep Cycles

Consistency (A.K.A. Reproducibility)
Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect. Furthermore, in accordance with the law of large numbers (LLN), the predictive power and accuracy of these results will continually grow over time. 649 paired data points were used in this analysis. Assuming that the relationship is merely coincidental, as the participant independently modifies their Acetyl L-carnitine intake values, the observed strength of the relationship will decline until it is below the threshold of significance. To it another way, in the case that we do find a spurious correlation, suggesting that banana intake improves mood for instance, one will likely increase their banana intake. Due to the fact that this correlation is spurious, it is unlikely that you will see a continued and persistent corresponding increase in mood. So over time, the spurious correlation will naturally dissipate.

Specificity
Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.

Temporality
The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay). The confidence in a causal relationship is bolstered by the fact that time-precedence was taken into account in all calculations.

Biological Gradient
Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.

Plausibility
A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel. Based on our responses so far, 1 humans feel that there is a plausible mechanism of action and 0 feel that any relationship observed between Acetyl L-carnitine intake and Sleep Cycles is coincidental.

Coherence
Coherence between epidemiological and laboratory findings increases the likelihood of an effect. It will be very enlightening to aggregate this data with the data from other participants with similar genetic, diseasomic, environmentomic, and demographic profiles.

Experiment
All of human life can be considered a natural experiment. Occasionally, it is possible to appeal to experimental evidence.

Analogy
The effect of similar factors may be considered.

Relationship Statistics

Property Value
Cause Variable Name Acetyl L-carnitine intake
Effect Variable Name Sleep Cycles
Sinn Predictive Coefficient 0.0079943755734176
Confidence Level high
Confidence Interval 0.99951733606609
Forward Pearson Correlation Coefficient 0.0442
Critical T Value 1.6815
Total Acetyl L-carnitine intake Over Previous 7 days Before ABOVE Average Sleep Cycles 12 milligrams
Total Acetyl L-carnitine intake Over Previous 7 days Before BELOW Average Sleep Cycles 5602.3340248963 milligrams
Duration of Action 7 days
Effect Size very weakly positive
Number of Paired Measurements 649
Optimal Pearson Product 0.021414922411843
P Value 0.025360547820652
Statistical Significance 0.51775001361966
Strength of Relationship 0.99951733606609
Study Type population
Analysis Performed At 2019-04-06
Number of Participants 2

Acetyl L-carnitine Statistics

Property Value
Variable Name Acetyl L-carnitine
Aggregation Method SUM
Analysis Performed At 2019-04-02
Duration of Action 7 days
Kurtosis 29.416298109179
Mean 10511.81553 milligrams
Median 10500.04079 milligrams
Minimum Allowed Value 0 milligrams
Number of Correlations 129
Number of Measurements 1248
Onset Delay 30 minutes
Standard Deviation 460.13578482894
Unit Milligrams
UPC 885222361371
Variable ID 1247
Variance 713125.42437298

Sleep Cycles Statistics

Property Value
Variable Name Sleep Cycles
Aggregation Method SUM
Analysis Performed At 2019-04-05
Duration of Action 7 days
Kurtosis 11.119898057479
Mean 4.4567415283019 event
Median 4.1037735849057 event
Minimum Allowed Value 0 event
Number of Correlations 524
Number of Measurements 5390
Onset Delay 0 seconds
Standard Deviation 2.2339572293443
Unit Event
Variable ID 1888
Variance 6.3592307582272

Tracking Acetyl L-carnitine

Record your Acetyl L-carnitine daily in the reminder inbox or using the interactive web or mobile notifications.

Tracking Sleep Cycles

Get Sleep as Android here and use it to record your Sleep Cycles. Once you have a Sleep as Android account, you can import your data from the Import Data page. This individual's data will automatically be imported and analyzed.
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https://lh6.googleusercontent.com/-BHr4hyUWqZU/AAAAAAAAAAI/AAAAAAAIG28/2Lv0en738II/photo.jpg Principal Investigator - Mike Sinn